Probiotics are living microorganism which are incorporated with diets that benefits the intestine in populating the intestine with good bacteria and modulate the condition within the gastrointestinal tract. The use of probiotics is important and become more important in those poultry birds in which stable and good intestinal bacteria have not developed in the gut. We can mix the probiotics in the poultry feed or with the drinking water and by adding this we can populate the intestine with good bacteria and decrease the extent of pathogen colonization. In modern poultry farming the use of probiotics in the poultry feed provides preventing measures from the growth of pathogens which cause low health and diseases. The combination of probiotics with prebiotics which is known as symbiotic help in nourishing the good bacteria in the gut and achieve better result. Prebiotic are actually non-digestive feed additive containing natural dietary fibers like (fructooligsaccharidesFOS) which stimulates the growth and activity of good bacteria in the colon thus improving the health. We use Anfazyme Premium Layer Feed Enzyme which helps in developing goof bacteria in the gut and promotes a healthy growth. It contains probiotics with poultry feed enzymes that helps in better digestion of the feed and promotes better absorption of nutrients of the feed and speed up the metabolic process and provides energy to the body for better and healthy body. This poultry feed probiotics (Anfazyme Premium) contains probiotics like lactobacillus, Bacillus Subtills and in enzymes like Xylanase, phytase, protease which are major poultry feed enzymes that are commercially used.